Does CBD Oil Interact With Anti-Inflammatory Drugs?

Does CBD Oil Interact With Anti-Inflammatory Drugs?


Does CBD Oil Interact With Anti-Inflammatory Drugs?

Some medications used to treat pain, anxiety and other issues are metabolized by an enzyme in the liver called cytochrome P450. Taking CBD interferes with this enzyme, which may prevent the drugs from being metabolized properly or can increase the amount of the drugs in the body, resulting in side effects. URL


Xanax is a benzodiazepine (sedative) medication that is commonly used to treat panic disorders, anxiety and depression. Taking CBD interferes with CYP3A4, which is responsible for breaking down Xanax and other benzodiazepines.


Epidiolex is an FDA-approved prescription product that is designed to treat seizures. It is available in a high concentration of cannabidiol, and it has been found to help improve seizure symptoms and control them for patients with epilepsy.

The Safety of Using CBD Oil with Anti-Inflammatory Drugs: What You Need to Know

CBD interferes with CYP3A4 and CYP2C9, which are responsible for breaking down certain antidepressants, including fluoxetine, clomipramine, amitriptyline, tamoxifen, and sertraline. Using CBD with antidepressants may decrease the effectiveness of the antidepressants and cause side effects such as drowsiness, dizziness, and difficulty concentrating.


While more research is needed on the use of CBD with diabetes, a 2006 study in Autoimmunity showed that it reduced the incidence of type 2 diabetes in animals. It also decreased the blood glucose level of animals with the condition.


Studies have shown that taking CBD with blood-thinning drugs like warfarin can increase the risk of bleeding. The combination can also raise abnormal liver enzyme levels and induce tiredness, so it is important to check with your doctor if you are taking both drugs.

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